A rare system indeed, and not previously well-understood, but new information has been dug up. See this thread on stardot.
This was a development system for 6502 systems. Up to six Developers could use the es-65 to assemble programs and also (with additional hardware) do in-circuit debugging on the target! After finalizing the code an EPROM could be programmed on the es-65 (with the second serial ports) and the work was finished. I think this is great stuff from 1980.
Robert_O is in contact with the original engineers, and sharing notes and reverse-engineered schematics on bitbucket.
Back in the days of G+ we posted about this machine here.
@oscarv has one of these machines: